M&A / Property
SciSparc: Neurothera Labs Announces Israeli Patent Application in Collaboration with Clearmind Medicine for Novel Non-Hallucinogenic Neuroplastogen Treatment for Depression

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Executive Summary
- SciSparc Ltd., which holds a ~75% controlling interest in NeuroThera Labs Inc., announced the filing of an Israeli patent application for a novel combination therapy (MEAI + N‑Acylethanolamines such as PEA) targeting depression, developed with Clearmind Medicine Inc.
- The filing expands the joint IP portfolio to 13 patents covering MEAI/PEA combinations for multiple CNS and addiction indications (alcohol use disorder, cocaine addiction, obesity/weight loss, and depression).
- The announcement underscores SciSparc’s strategic focus on cannabinoid‑based therapeutics and its effort to build a robust pipeline of CNS treatments.
Key Details
- Patent Filing: Israeli patent application for the combination therapy of 5‑methoxy‑2‑aminoindane (MEAI) and N‑Acylethanolamines (e.g., Palmitoylethanolamide, PEA).
- Collaboration Partner: Clearmind Medicine Inc. (Nasdaq: CMND).
- Therapeutic Target: Depression; the same platform is being explored for alcohol use disorder, cocaine addiction, obesity/weight loss, and other CNS disorders.
- Ownership Structure: SciSparc holds approximately 75% of NeuroThera Labs Inc., the entity filing the patent.
- IP Portfolio Size: 13 patents filed to date under the SciSparc‑NeuroThera‑Clearmind collaboration.
- Preclinical Support: Data indicate MEAI’s efficacy in reducing addictive behaviors while preserving normal reward pathways.
- Market Context: WHO data (Aug 2025) cite ~332 million people living with major depressive disorder worldwide (~5.7% of adults).
Notable Quotes
(No direct quotes were provided in the release.)
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Jun 30, 2026 · 18:00