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AII 19.25 +3.9% GGA 5.95 +12.3% VM 0.140 +3.7% GSR 0.365 +1.4% QCX 0.195 +0.0% EAU 0.085 +0.0% MCM 0.310 +0.0% BAT 0.100 +5.3% SFR 0.370 +68.2% FFU 0.125 +4.2% TVI 0.045 −10.0% ZNX 0.080 +0.0% TSK 1.06 +0.9% OMM 0.050 +0.0% EMO 0.320 −7.2% MDM 0.060 +0.0% AII 19.25 +3.9% GGA 5.95 +12.3% VM 0.140 +3.7% GSR 0.365 +1.4% QCX 0.195 +0.0% EAU 0.085 +0.0% MCM 0.310 +0.0% BAT 0.100 +5.3% SFR 0.370 +68.2% FFU 0.125 +4.2% TVI 0.045 −10.0% ZNX 0.080 +0.0% TSK 1.06 +0.9% OMM 0.050 +0.0% EMO 0.320 −7.2% MDM 0.060 +0.0%
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Updated MDNA11 Clinical Data from the ABILITY-1 Study to be Presented at the European Society for Medical Oncology (ESMO) Immuno-Oncology Congress 2025

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Executive Summary

  • Medicenna Therapeutics announced that updated Phase 1/2 ABILITY‑1 clinical data for MDNA11 will be presented at the ESMO Immuno‑Oncology Congress 2025 in London (Dec 10‑12, 2025).
  • The presentation will cover interim analysis of MDNA11 as monotherapy and in combination with pembrolizumab in advanced solid tumors.
  • A copy of the presentation will be posted on Medicenna’s website after the conference.

Key Details

  • Presentation Title: “ABILITY‑1, a phase 1/2 of MDNA11, a next‑generation IL‑2 agonist, alone or with pembrolizumab in advanced solid tumors: interim analysis.”
  • Presenter: Dr. André Mansinho, MD MSc, Assistant Professor, Faculty of Medicine, University of Lisbon (principal investigator of the ABILITY‑1 study).
  • Date & Venue: December 10, 2025 at the European Society for Medical Oncology (ESMO) Immuno‑Oncology Congress 2025, London, United Kingdom.
  • Study Context: Phase 1/2 ABILITY‑1 Study evaluating MDNA11 (a next‑generation IL‑2 agonist) as monotherapy and in combination with pembrolizumab in patients with advanced solid tumors.
  • Post‑Event Access: A copy of the presentation will be made available on Medicenna’s “Events and Presentations” web page after the congress concludes.

Notable Quotes

(No direct quotes were provided in the release.)

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